Basic constituent of lecithin. Found in many plants and animal organs, e.g. bile, brain, yolk of eggs, hops, belladonna, strophanthus. Usually made synthetically from trimethylamine and ethylene chlorohydrin or ethylene oxide: Blackett, Soliday, US 2774759 (1956 to Am. Cyanamid). Review: T. H. Jukes in Kirk-Othmer Encyclopedia of Chemical Technology vol. 6 (Wiley-Interscience, New York, 3rd ed., 1979) pp 19-28.