2325. Citrazinic Acid

Nomenclature

CAS number: 99-11-6
1,2-Dihydro-6-hydroxy-2-oxo-4-pyridinecarboxylic acid; 2,6-dihydroxyisonicotinic acid; 2,6-dihydroxy-4-pyridinecarboxylic acid.
C6H5NO4; mol wt 155.11.
C 46.46%, H 3.25%, N 9.03%, O 41.26%.

Description and references

Prepn from citric acid with aq NH3 at 140-160° under pressure: Bavley, Hamilton, US 2729647 (1956 to Pfizer). Purification: Bavley et al., US 2738352 (1956 to Pfizer).

Chemical structure

Properties

Yellowish powder with a greenish tinge; carbonizes above 300° without melting. Ultrapure material which is white or colorless, has been prepared. Almost insol in water; slightly sol in hot HCl; sol in alkali hydroxide or carbonate solns. Alkaline solns turn blue on standing.