2454. Cocaethylene

Nomenclature

CAS number: 529-38-4
[1R-(exo,exo)]-3-(Benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid ethyl ester; ecgonine ethyl ester benzoate (ester); O-benzoyl-l-ecgonine ethyl ester; ethylbenzoylecgonine; Homocaine.
C18H23NO4; mol wt 317.38.
C 68.12%, H 7.30%, N 4.41%, O 20.16%.

Description and references

Homolog of cocaine. Prepn: Merck, Ber. 18, 2952 (1885); Einhorn, ibid. 21, 47 (1888).

Chemical structure

Properties

Prisms from alcohol, mp 109°. Almost insol in water. Sol in alcohol, ether.

Therapeutic Category

Anesthetic (local).

Keywords

Anesthetic (Local)