2549. Corypalmine

Nomenclature

CAS number: 6018-40-2
5,8,13,13a-Tetrahydro-2,9,10-trimethoxy-6H-dibenzo[a,g]quinolizin-3-ol; 2,9,10-trimethoxyberbin-3-ol; 3-hydroxy-2,9,10-trimethoxyberbine; tetrahydrojatrorrhizine.
C20H23NO4; mol wt 341.40.
C 70.36%, H 6.79%, N 4.10%, O 18.75%.

Description and references

In Corydalis cava (L.) Schweigg & K"orte (C. tuberosa D.C.) and other varieties of Corydalis, Fumariaceae. Synthesis of dl-corypalmine: Govindachari et al., Ber. 92, 1654 (1959).

Chemical structure

Derivative

d-Form.

Properties

Small crystals, mp 236°. [α]D16 +280° (chloroform). Insol in water; sol in alcohol and chloroform: Sp"ath et al., Ber. 56, 878 (1923); 58, 2133 (1925); 60, 383 (1927).

Derivative

l-Form.

Properties

Crystals from chloroform-methanol, mp 246° (in vac): Manske, Can. J. Res. 20B, 57 (1942); 21B, 111 (1943).

Derivative

dl-Form.

Properties

Crystals from methanol, mp 207°.