2591. Cropropamide

Nomenclature

CAS number: 633-47-6
N-[1-[(Dimethylamino)carbonyl]propyl]-N-propyl-2-butenamide; N-(1-dimethylcarbamoylpropyl)-N-propylcrotonamide; α-(N′-crotonyl-N′-propyl)amino-N,N-dimethylbutyramide.
C13H24N2O2; mol wt 240.34.
C 64.97%, H 10.07%, N 11.66%, O 13.31%.

Description and references

Prepn: Martin, Gysin, US 2447587 (1948 to Geigy).

Chemical structure

Properties

Liquid, bp0.25 128-130°. Easily sol in water, ether.

Derivative

Combination with crotethamide.

Nomenclature

CAS number: 8015-51-8
Prethcamide; Micoren (Novartis); Respirot (Novartis).

Therapeutic Category

Combination as respiratory stimulant.

Keywords

Respiratory Stimulant