2854. Decoquinate

Nomenclature

CAS number: 18507-89-6
6-(Decyloxy)-7-ethoxy-4-hydroxy-3-quinolinecarboxylic acid ethyl ester; ethyl 6-(n-decyloxy)-7-ethoxy-4-hydroxyquinoline-3-carboxylate; M & B 15497; Deccox (Alpharma).
C24H35NO5; mol wt 417.54.
C 69.04%, H 8.45%, N 3.35%, O 19.16%.

Description and references

Anticoccidial quinolone; feed additive for livestock. Description of compd: Ball et al., Chem. Ind. (London) 1968, 56. Prepn: BE 698305; M. Davis et al., US 3485845 (1966, 1969 both to May & Baker). Metabolism and residue studies: E. M. Craine et al., J. Agric. Food Chem. 19, 1228 (1971); R. F. Kouba et al., ibid. 1234. Evaluation in experimental ruminant cryptosporidiosis: R. Mancassola et al., Vet. Parasitol. 69, 31 (1997). Mode of action study: E. Del Cacho et al., Int. J. Parasitol. 36, 1515 (2006).

Chemical structure

Properties

Cream to buff-colored fine amorphous powder. mp 244-246°. Insol in water.

Therapeutic Category (Veterinary)

Coccidiostat.