2901. Deoxycorticosterone Acetate

Nomenclature

CAS number: 56-47-3
21-Acetyloxypregn-4-ene-3,20-dione; 21-hydroxypregn-4-ene-3,20-dione 21-acetate; 11-deoxycorticosterone acetate; cortexone acetate; desoxycorticosterone acetate; deoxycortone acetate; desoxycortone acetate; DCA; Cortate (Schering); Cortiron (Schering AG); Decosteron (Kwizda); Doca (Organon); Dorcostrin (Dorsey); Percorten (Novartis); Syncortyl (Roussel Diamant).
C23H32O4; mol wt 372.50.
C 74.16%, H 8.66%, O 17.18%.
Chemical structure

Properties

Orthorhombic needles from alcohol, stable in air, mp 154-160°. Sublimes in high vacuum. [α]D20 +168 to +176° (dioxane). Slightly sol in alcohol, methanol, acetone, ether, dioxane, propylene glycol (10 mg/ml), vegetable oils. Practically insol in water.

Therapeutic Category

Mineralocorticoid.

Therapeutic Category (Veterinary)

Adrenocortical steroid, mineralocorticoid.

Keywords

Mineralocorticoid