2997. Diazoacetic Ester

Nomenclature

CAS number: 623-73-4
2-Diazoacetic acid ethyl ester; ethyl diazoacetate; ethyl diazoethanoate.
C4H6N2O2; mol wt 114.10.
C 42.11%, H 5.30%, N 24.55%, O 28.04%.

Description and references

Prepd by the action of sodium nitrite on glycine ethyl ester hydrochloride: Curtius J. Prakt. Chem. [2] 38, 396 (1888); Silberrad, J. Chem. Soc. 81, 600 (1902); Womack, Nelson, Org. Synth. 24, 56 (1944).

Chemical structure

Properties

Yellow oil. Pungent odor. Very volatile. Explosive. Distillation, even under reduced pressure, is dangerous. mp -22°. d417.6 1.0852. bp5 42°; bp12 45°; bp88 85-86°; bp720 140-141°. nD17.6 1.4588. Slightly sol in water. Neutral reaction. Volatile with steam, ether, and benzene vapors. Miscible with alcohol, benzene, ligroin, ether. Explodes on contact with concd H2SO4.