3244. N,N-Dimethylglycine

Nomenclature

CAS number: 1118-68-9
2-(Dimethylamino)acetic acid; N-methylsarcosine; DMG.
C4H9NO2; mol wt 103.12.
C 46.59%, H 8.80%, N 13.58%, O 31.03%.

Description and references

Prepn: H. T. Clarke et al., J. Am. Chem. Soc. 55, 4571 (1933); D. E. Pearson, J. D. Bruton, ibid. 73, 864 (1951). Mutagenicity study: N. Colman et al., Proc. Soc. Exp. Biol. Med. 164, 9 (1980). Constituent of some products sold in the U.S. as “pangamic acid”.

Chemical structure

Properties

Hygroscopic crystals, mp 157-160°.

Derivative

Hydrochloride.

Nomenclature

CAS number: 2491-06-7
C4H9NO2.HCl; mol wt 139.58.
C 34.42%, H 7.22%, N 10.03%, O 22.93%, Cl 25.40%.

Properties

mp 189-190°. Sol in alc, water. Insol in chloroform, acetone.