3336. Dipin
Nomenclature
CAS number: 738-99-8
1,4-Bis[bis(1-aziridinyl)phosphinyl]piperazine; 1,4-piperazinediylbis[bis(1-aziridinyl)phosphine oxide]; piperazine-1,4-bis(N,N′-diethylenephosphonediamide); tetraethyleneimidopiperazine-N,N′-diphosphoric acid. C12H24N6O2P2; mol wt 346.31.
C 41.62%, H 6.99%, N 24.27%, O 9.24%, P 17.89%.
Description and references
Alkylating agent; exptl antineoplastic. Prepn: Kropacheva et al., Zh. Obshch. Khim. 30, 3584 (1960), C.A. 55, 18695c (1961). Spectrophotometric determn: L. Kh. Kartashova, E. M. Salomatin, Farmatsiya (Moscow) 33, 72 (1983), C.A. 102, 119736j (1985). Metabolism in rats: V. V. Chistyakov et al., Khim. Farm. Zh. 21, 398 (1987), C.A. 107, 146734s (1987).
