3653. Ergoloid Mesylates

Nomenclature

CAS number: 8067-24-1
Dihydroergotoxine monomethanesulfonate (salt); co-dergocrine mesylate; CCK-179; Circanol (3M); Coristin (San Carlo); Dacoren (Nattermann); DCCK (Rentschler); Decril (Mediolanum); Dulcion (Dulcis); Ergodesit (Graf); Ergohydrin (Streuli); Ergoplus (Formosan); Hydergine (Sandoz); Lysergin (Toa Eiyo); Novofluen (Engelhard KG); Orphol (Sanofi); Pérénan (Sanofi Winthrop); Progeril (Midy); Redergin (Lek); Sponsin (Farmasan); Trigot (BMS).

Description and references

Hydrogenated ergot alkaloids, specifically an equiproportional mixture of dihydroergocornine methanesulfonate, dihydroergocristine methanesulfonate and α- and β-dihydroergocryptine methanesulfonate in the ratio of 1.5-2.5:1. Neuropharmacological investigations: D. M. Loew et al., Postgrad. Med. J. 52, Suppl. 1, 40 (1976).

Chemical structure

Derivative

Dihydroergocristine methanesulfonate.

Nomenclature

CAS number: 24730-10-7
Decme (Spitzner); Defluina (Simes); Enirant (Desitin); Insibrin (Byk-Liprandi); Nehydrin (TAD); Simactil (Rorer); Unergol (Poli).
C36H45N5O8S; mol wt 707.84.
C 61.09%, H 6.41%, N 9.89%, O 18.08%, S 4.53%.

Therapeutic Category

α-Adrenergic blocker (treatment of impaired mental function in the elderly).

Keywords

α-Adrenergic Blocker