3682. Erythromycin Acistrate

Nomenclature

CAS number: 96128-89-1
Erythromycin 2′-acetate octadecanoate (salt); octadecanoic acid compd with erythromycin 2′-acetate; 2′-acetylerythromycin stearate; Erasis (Orion).
C57H105NO16; mol wt 1060.44.
C 64.56%, H 9.98%, N 1.32%, O 24.14%.
C39H69NO14.CH3(CH2)16COOH.

Description and references

Ester prodrug of erythromycin, q.v. Prepn: M. L. A. Marvola et al., BE 901411; E. J. Honkanen et al., US 4599326 (1985, 1986 both to Orion-yhtym"a Oy). Pharmacology, toxicity and clinical studies: J. Antimicrob. Chemother. 21, Suppl D, 1-122 (1988). For structure see Erythromycin.

Therapeutic Category

Antibacterial.

Keywords

Antibacterial (Antibiotics); Macrolides