3684. Erythromycin Glucoheptonate

Nomenclature

CAS number: 23067-13-2
d-glycero-d-gulo-Heptonic acid compd with erythromycin (1:1); erythromycin glucoheptonic acid salt; erythromycin gluceptate; Ilotycin Gluceptate (Lilly).
C44H81NO21; mol wt 960.11.
C 55.04%, H 8.50%, N 1.46%, O 34.99%.
C37H67NO13.C7H14O8.

Description and references

Semi-synthetic macrolide antibiotic. Prepn: Shepler, US 2852429 (1958 to Lilly).

Properties

Crystals, mp 95-140°. Freely sol in water, alcohol, dioxane, acetone, propylene glycol. Practically insol in ether, carbon tetrachloride, toluene, benzene. 2% aq solns are levorotatory and have a pH of 6.0 to 7.5.

Therapeutic Category

Antibacterial.

Keywords

Antibacterial (Antibiotics); Macrolides