3740. Ethirimol

Nomenclature

CAS number: 23947-60-6
5-Butyl-2-(ethylamino)-6-methyl-4(1H)-pyrimidinone; 2-ethylamino-4-methyl-5-n-butyl-6-hydroxypyrimidine; PP-149; Milstem (Zeneca); Milgo (Zeneca); Milcurb Super (Zeneca).
C11H19N3O; mol wt 209.29.
C 63.13%, H 9.15%, N 20.08%, O 7.64%.

Description and references

Prepn: B. K. Snell et al., ZA 6701373; eidem, US 3980781 (1968, 1976 both to ICI). Systemic fungicidal activity: R. M. Bebbington, Chem. Ind. (London) 1969, 1512; K. J. Bent, Ann. Appl. Biol. 66, 103 (1970). Metabolism and mode of action: A. Calderbank, Acta Phytopathol. 6, 355 (1971).

Chemical structure

Properties

Crystalline solid, mp 159-160°. Vapor pressure at 25°: 2 × 10-6 mm Hg. Soly in water at 25°: 200 mg/l. Sol in chloroform, trichloroethylene, aq solns of strong acids and bases. Slightly sol in ethanol; sparingly sol in acetone. LD50 orally in rats: 4000 mg/kg (Bebbington).

Use

Fungicide.