3755. Ethoxzolamide

Nomenclature

CAS number: 452-35-7
6-Ethoxy-2-benzothiazolesulfonamide; ethoxyzolamide; Ethamide (Allergan); Glaucotensil (Farmila).
C9H10N2O3S2; mol wt 258.32.
C 41.85%, H 3.90%, N 10.84%, O 18.58%, S 24.83%.

Description and references

Carbonic anhydrase inhibitor. Prepn: GB 795174; J. Korman, US 2868800 (1958, 1959 both to Upjohn).

Chemical structure

Properties

Crystals from ethyl acetate + Skellysolve B, mp 188-190.5°.

Therapeutic Category

Diuretic.

Therapeutic Category (Veterinary)

Diuretic.

Keywords

Carbonic Anhydrase Inhibitor; Diuretic; Sulfonamide Derivatives