3763. N-Ethylamphetamine

Nomenclature

CAS number: 457-87-4
N-Ethyl-α-methylbenzeneethanamine; N-ethyl-α-methylphenethylamine; N-ethyl-ω-phenylisopropylamine; 2-ethylamino-1-phenylpropane.
C11H17N; mol wt 163.26.
C 80.92%, H 10.50%, N 8.58%.

Description and references

Prepn: Keil, Dobke, DE 767263 (1952 to Theodor H. Temmler); Leonard et al., J. Am. Chem. Soc. 80, 4858 (1958). Separation of isomers: GB 814339 (1959 to Sterling Drug).

Chemical structure

Properties

bp14 104.5-106°. nD25 1.4986.

Derivative

Hydrochloride.

Nomenclature

CAS number: 1858-47-5
MG-19973; Apetinil-Depo (Drossapharm).
C11H17N.HCl; mol wt 199.72.
C 66.15%, H 9.08%, N 7.01%, Cl 17.75%.

Derivative

d-Form hydrochloride.
C11H17N.HCl; mol wt 199.72.
C 66.15%, H 9.08%, N 7.01%, Cl 17.75%.

Properties

mp 154-156°. [α]D15 +17.2° (c = 2 in water).

Derivative

l-Form hydrochloride.
C11H17N.HCl; mol wt 199.72.
C 66.15%, H 9.08%, N 7.01%, Cl 17.75%.

Properties

mp 155-156°. [α]D25 -17.3° (c = 2 in water).

Note

This is a controlled substance (stimulant): 21 CFR, 1308.11.

Therapeutic Category

Anorexic.

Keywords

Anorexic; CNS Stimulant