3812. Ethylidene Dicoumarol

Nomenclature

CAS number: 1821-16-5
3,3′-Ethylidenebis[4-hydroxy-2H-1-benzopyran-2-one]; 3,3′-ethylidenebis(4-hydroxycoumarin); 3,3-ethylidenebis(4-oxycoumarin); Pertrombon.
C20H14O6; mol wt 350.32.
C 68.57%, H 4.03%, O 27.40%.

Description and references

Prepn: Jansen, Jensen, Z. Phys. Chem. 277, 66 (1943); Sullivan et al., J. Am. Chem. Soc. 66, 2288 (1943); Stahmann et al., ibid. 67, 900 (1944); AT 196874 (1958 to Spofa), C.A. 52, 10212d (1958); Fucik, CS 85918 (1957), C.A. 52, 2930d (1958).

Chemical structure

Properties

Crystals from ethanol + dioxane, mp 178°.

Derivative

Dibenzoate.
C34H22O8; mol wt 558.53.
C 73.11%, H 3.97%, O 22.92%.

Properties

mp 209-210°.

Therapeutic Category

Anticoagulant.

Keywords

Anticoagulant