3822. N-Ethylmaleimide

Nomenclature

CAS number: 128-53-0
1-Ethyl-1H-pyrrole-2,5-dione.
C6H7NO2; mol wt 125.13.
C 57.59%, H 5.64%, N 11.19%, O 25.57%.

Description and references

Prepd by heating N-ethylmaleamic acid in paraffin: Marrian, J. Chem. Soc. 1949, 1515.

Chemical structure

Properties

Crystals, mp 45°. Lacrimator when liquid.

Caution

Strong irritant.

Use

In cancer research (possible antimitotic activity.)