3834. Ethylnorepinephrine

Nomenclature

CAS number: 536-24-3
4-(2-Amino-1-hydroxybutyl)-1,2-benzenediol; α-(1-aminopropyl)-3,4-dihydroxybenzyl alcohol; α-(1-aminopropyl)protocatechuyl alcohol; 1-(3,4-dihydroxyphenyl)-2-aminobutanol; 1-(3,4-dihydroxyphenyl)-1-hydroxy-2-aminobutane; ethylnoradrenaline; ethylnorsuprarenin; E.N.E.; E.N.S..
C10H15NO3; mol wt 197.23.
C 60.90%, H 7.67%, N 7.10%, O 24.34%.

Description and references

Prepd by catalytic hydrogenolysis of α-benzhydrylamino-3,4-dibenzyloxybutyrophenone-HCl: Suter, Ruddy, J. Am. Chem. Soc. 66, 747 (1944); US 2431285 (1947 to Winthrop-Stearns).

Chemical structure

Derivative

Hydrochloride.

Nomenclature

CAS number: 3198-07-0
Bronkephrine (Sterling Winthrop).
C10H15NO3.HCl; mol wt 233.69.
C 51.40%, H 6.90%, N 5.99%, O 20.54%, Cl 15.17%.

Properties

Crystals, dec 199-200°. Soluble in water. Marketed as an 0.2% aq soln.

Therapeutic Category

Bronchodilator.

Keywords

β-Adrenergic Agonist; Bronchodilator; Ephedrine Derivatives