3862. Etidocaine

Nomenclature

CAS number: 36637-18-0
N-(2,6-Dimethylphenyl)-2-(ethylpropylamino)butanamide; 2-(ethylpropylamino)-2′,6′-butyroxylidide.
C17H28N2O; mol wt 276.42.
C 73.87%, H 10.21%, N 10.13%, O 5.79%.

Description and references

Prepn: H. J. F. Adams et al., DE 2162744; eidem, US 3812147 (1972, 1974 both to Astra). Activity and toxicity studies: eidem, J. Pharm. Sci. 61, 1829 (1972).

Chemical structure

Derivative

Hydrochloride.

Nomenclature

CAS number: 36637-19-1
W-19053; Duranest (Astra).
C17H28N2O.HCl; mol wt 312.88.
C 65.26%, H 9.34%, N 8.95%, O 5.11%, Cl 11.33%.

Properties

Crystals from abs ethanol-ether and isopropanol-isopropylether, mp 203-203.5°. LD50 in female mice (mg/kg): 6.7 i.v.; 99 s.c. (Adams, 1972).

Therapeutic Category

Anesthetic (local).

Keywords

Anesthetic (Local)