3906. Evening Primrose Oil

Nomenclature

EPO.

Description and references

Seed oil of the evening primrose, Oenothera biennis L., Onagraceae, which contains approx 72% linoleic acid and approx 9% γ-linolenic acid, q.q.v., as the two main constituents. Unique among vegetable oils because of its high content of γ-linolenic acid. Effect on prostaglandin biosynthesis in rats: B. A. Sch"olkens et al., Prostaglandins Leukotrienes Med. 8, 273 (1982). Clinical studies in atopic eczema: C. R. Lovell et al., Lancet 1, 278 (1981); S. Wright, J. L. Burton, ibid. 2, 1120 (1982); P. L. Biagi et al., Drugs Exp. Clin. Res. 14, 285 (1988). Ingredient in cosmetics for aging skin: J. P. Marty, DE 3447618 (1985 to Roussel-UCLAF), C.A. 103, 146984r (1985). Brief review including discussion of uses: A. J. Barber, Pharm. J. 240, 723-725 (1988).

Properties

Clear, golden yellow oil. d15 0.9283. nD25 1.4782. Sapon. no. 287.8. Iodine no. 154.8.

Note

Evening primrose oil products include Efamol, Efamast, Epogam.

Use

Dietary supplement.

Therapeutic Category

In treatment of atopic eczema and mastaglia.

Keywords

Antieczematic