3944. Febantel

Nomenclature

CAS number: 58306-30-2
[[2-[(Methoxyacetyl)amino]-4-(phenylthio)phenyl]carbonimidoyl]biscarbamic acid dimethyl ester; dimethyl [[2-(2-methoxyacetamido)-4-(phenylthio)phenyl]imidocarbonyl]dicarbamate; Bay Vh 5757; Bay h 5757; Rintal (Bayer).
C20H22N4O6S; mol wt 446.48.
C 53.80%, H 4.97%, N 12.55%, O 21.50%, S 7.18%.

Description and references

Prepn: H. Koelling et al., DE 2423679; eidem, US 3993682 (1975, 1976 both to Bayer). Anthelmintic efficacy: H. Wollweber et al., Arzneim.-Forsch. 28, 2193 (1977); H. Thomas, Res. Vet. Sci. 25, 290 (1978). Safety evaluation in horses: J. A. Shmidl, Vet. Med. Small Anim. Clin. 73, 775 (1978).

Chemical structure

Properties

Crystals, mp 129-130°.

Therapeutic Category (Veterinary)

Anthelmintic.