3966. Fencamfamine

Nomenclature

CAS number: 1209-98-9
N-Ethyl-3-phenylbicyclo[2.2.1]heptan-2-amine; N-ethyl-3-phenyl-2-norbornanamine; 2-ethylamino-3-phenylnorcamphane; 2-phenyl-3-ethylaminonorbornane; 2-ethylamino-3-phenylnorbornane; 2-ethylamino-3-phenylbicyclo[2.2.1]heptane; Euvitol (Allen & Hanburys).
C15H21N; mol wt 215.33.
C 83.67%, H 9.83%, N 6.50%.

Description and references

Prepd from 3-amino-2-phenylnorbornane and acetaldehyde followed by hydrogenation in the presence of PtO2: Thesing et al., DE 1110159 (1961 to E. Merck), C.A. 56, 2352g (1962). Pharmacology: R. Hotovy et al., Arzneim.-Forsch. 11, 20 (1961).

Chemical structure

Properties

bp0.1 128-131°.

Derivative

Hydrochloride.

Nomenclature

CAS number: 2240-14-4
H-610.
C15H21N.HCl; mol wt 251.79.
C 71.55%, H 8.81%, N 5.56%, Cl 14.08%.

Description and references

Principal ingredient of Reactivan which also contains vitamins B1, B6, B12 and C.

Properties

Crystals from acetone, mp 192°. Freely sol in water, ethanol, methanol, chloroform; slightly sol in benzene. Practically insol in ether. LD50 in mice, rats (mg/kg): 135.0, 113.0 orally; 85.5, 68.5 s.c.; 15.7, 23.5 i.v. (Hotovy).

Note

This is a controlled substance (stimulant): 21 CFR, 1308.14.

Therapeutic Category

CNS stimulant.

Keywords

CNS Stimulant