4000. Fensulfothion

Nomenclature

CAS number: 115-90-2
Phosphorothioic acid O,O-diethyl O-[4-(methylsulfinyl)phenyl] ester; O,O-diethyl O-[p-(methylsulfinyl)phenyl] phosphorothioate; DMSP; Bay 25141.
C11H17O4PS2; mol wt 308.35.
C 42.85%, H 5.56%, O 20.75%, P 10.05%, S 20.80%.

Description and references

Organophosphate insecticide; cholinesterase inhibitor. Prepn: Homeyer, Schrader, BE 666012 (1965 to Bayer), C.A. 64, 20555f (1966). Acute toxicity and anticholinesterase activity: K. P. DuBois, F. Kinoshita, Toxicol. Appl. Pharmacol. 6, 78 (1964) DOI PubMed. HPLC determn in natural waters: Y. He, H. K. Lee, J. Chromatogr. A 1122, 7 (2006) DOI PubMed.

Chemical structure

Properties

Liquid. Poisonous. bp0.01 138-141°. LD50 in male, female rats (mg/kg): 5.5, 1.5 i.p.; 10.5, 2.2 orally; 30.0, 3.5 dermally; in male, female mice (mg/kg): 10.5, 7.0 i.p.; in male guinea pigs (mg/kg): 5.4 i.p., 9.0 orally (DuBois, Kinoshita).

Caution

Potential symptoms of overexposure are skin irritation; nausea, vomiting, abdominal cramps, diarrhea, salivation; headache, giddiness, vertigo, weakness; rhinorrhea, chest tightness; blurred vision, miosis; cardiac irregularities; muscle fasciculations; dyspnea. See NIOSH Pocket Guide to Chemical Hazards (DHHS/NIOSH 97-140, 1997) p 142.

Use

Nematocide; insecticide.