4041. Ferrous Bisglycinate
Nomenclature
CAS number: 20150-34-9
Bis(glycinato-κN,κO)iron; bisglycino-iron(II) chelate; Ferrochel (Albion). C4H8FeN2O4; mol wt 203.96.
C 23.56%, H 3.95%, Fe 27.38%, N 13.73%, O 31.38%.
Description and references
Nutritionally functional, totally reacted, metal amino acid chelate. Prepn: B. W. Fitzsimmons et al., Inorg. Chim. Acta 106, 109 (1985). Clinical evaluation of tolerability vs ferrous sulfate: M. Coplin et al., Clin. Ther. 13, 606 (1991); of iron bioavailability: M. Layrisse et al., J. Nutr. 130, 2195 (2000). Clinical study in iron deficiency anemia in infants: O. Pineda, H. D. Ashmead, Nutrition 17, 381 (2001); in children: L. H. S. Miglioranza et al., ibid. 19, 419 (2003). Toxicity study: R. B. Jeppsen, J. F. Borzelleca, Food Chem. Toxicol. 37, 723 (1999). Reviews: M. R. Motyka, Agro-Food-Ind. Hi-Tech 12, 6-8, 14-16 (2001).
Properties
Off-white solid. LD50 orally in rats: 560 mg iron/kg (Jeppsen).Therapeutic Category
Hematinic.
Keywords
Hematinic