4154. Fluometuron

Nomenclature

CAS number: 2164-17-2
N,N-Dimethyl-N′-[3-(trifluoromethyl)phenyl]urea; 1,1-dimethyl-3-(α,α,α-trifluoro-m-tolyl)urea; N-(3-trifluoromethylphenyl)-N′,N′-dimethylurea; Ciba 2059; Cotoran (Griffin); Cottonex (Makhteshim-Agan).
C10H11F3N2O; mol wt 232.20.
C 51.73%, H 4.77%, F 24.55%, N 12.06%, O 6.89%.

Description and references

Made by the reaction of dimethylamine on 3-trifluoromethylphenyl isocyanate: Abel, Chem. Ind. (London) 1957, 1106. Herbicidal preparations: Martin, Aebi, US 3134665 (1964 to Ciba). Toxicity data: R. Ben-Dyke et al., World Rev. Pest Control 9, 119 (1970). Review of carcinogenic risk: IARC Monographs 30, 245-253 (1983).

Chemical structure

Properties

Crystals, mp 163-164.5°. Soly in water at 25°: 80 ppm; sol in acetone, ethanol, isopropanol, DMF and other organic solvents. LD50 in rats (mg/kg): 8900 orally; in rabbits (mg/kg): >10,000 dermally (Ben-Dyke).

Use

Herbicide.