4196. Fluquinconazole

Nomenclature

CAS number: 136426-54-5
3-(2,4-Dichlorophenyl)-6-fluoro-2-(1H-1,2,4-triazol-1-yl)-4(3H)-quinazolinone; SN-597265; Castellan (AgrEvo); Jockey (AgrEvo); Vista (AgrEvo).
C16H8Cl2FN5O; mol wt 376.17.
C 51.09%, H 2.14%, Cl 18.85%, F 5.05%, N 18.62%, O 4.25%.

Description and references

Prepn: D. E. Green, A. Percival, EP 183458; eidem, US 4731106 (1985, 1988 both to Schering Agrochem). Chemical and biological properties: P. E. Russell et al., Brighton Crop Prot. Conf. - Pests Dis. 1992, 411. Fungicidal activity: G. Schnabel, L. Parisi, Acta Hortic. 466, 83 (1998). Efficacy against root disease, Take-all, in seed treatment: M. Wenz et al., Brighton Crop Prot. Conf. - Pests Dis. 1998, 907; in various crop stages: A. M. Lchel et al., ibid. 89. Review of residue analysis: R. Hnel et al., Nachrichtenbl. Dtsch. Pflanzenschutzdienst 50, 118 -126 (1998).

Chemical structure

Properties

Off-white particulate, mp 191.5-193°. Soly at 20° (g/l): water 0.001; acetone 44; xylene 10; ethanol 3; DMSO 150. Log P (octanol/water): 3.4. Vapor pressure (20°): 6.4 × 109 Pa. LD50 in male, female mice, male, female rats (mg/kg): 325, 180, 112, 112 orally; in male, female rats (mg/kg): 2679, 625 dermally (Russell).

Use

Agricultural fungicide primarily for cereal crops.