4670. Hesperetin

Nomenclature

CAS number: 520-33-2
(2S)-2,3-Dihydro-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one; 3′,5,7-trihydroxy-4′-methoxyflavanone; cyanidanon 4′-methyl ether 1626.
C16H14O6; mol wt 302.28.
C 63.57%, H 4.67%, O 31.76%.

Description and references

The aglucon of hesperidin. Prepd by hydrolysis of hesperidin or by synthesis: Shinoda, Kawagoye, C.A. 23, 2957 (1929); Seka, Prosche, Monatsh. Chem. 69, 284 (1936). Sepn of isomers: Arthur et al., J. Chem. Soc. 1956, 632. Structure and configuration: Arakawa, Nakazaki, Ann. 636, 111 (1960). See also Bioflavonoids.

Chemical structure

Properties

(±)-Form, prisms from alc, mp 226-228°. Freely sol in alc, moderately in ether. Slightly sol in water, chloroform, benzene; sol in dil alkalies. Precipitated by carbonates.