4716. Hippuric Acid

Nomenclature

CAS number: 495-69-2
N-Benzoylglycine; benzoylaminoacetic acid; benzamidoacetic acid.
C9H9NO3; mol wt 179.17.
C 60.33%, H 5.06%, N 7.82%, O 26.79%.

Description and references

Present in the urine of herbivorous animals; also in smaller amounts in human urine. Prepd from benzoyl chloride and glycine in NaOH soln: Ingersoll, Babcock, Org. Synth. coll. vol. II, 328 (1943).

Chemical structure

Properties

Crystals. mp 187-188°. One gram dissolves in about 250 ml cold water, 1000 ml chloroform, 400 ml ether, 60 ml amyl alcohol; slightly sol in cold, freely in hot alcohol or hot water; also sol in aq soln of sodium phosphate. Practically insol in benzene, carbon disulfide, petr ether.

Derivative

Ammonium salt.

Nomenclature

CAS number: 532-93-4
C9H12N2O3; mol wt 196.20.
C 55.09%, H 6.16%, N 14.28%, O 24.46%.

Properties

Crystals. Freely sol in water; sol in alcohol.

Derivative

Potassium salt monohydrate.

Nomenclature

CAS number: 6487-47-4
C9H8KNO3.H2O; mol wt 235.28.
C 45.94%, H 4.28%, K 16.62%, N 5.95%, O 27.20%.

Properties

Cryst powder. Very sol in water; sol in alcohol.