5037. Iodophors

Nomenclature

Tamed Iodine (West).

Description and references

The term iodophor may be applied to any product in which surface active agents (such as nonoxynol, q.v.) or polymers (such as polyvinylpyrrolidone, cf. povidone-iodine) act as carriers and solubilizing agents for iodine. Other examples: Biopal CVL-10; Dermevan; Idonyx; Iobac; Ioprep; Iosan; Kleenodyne; Rhudane; Showersan; Wescodyne; Westamine X. An iodophor usually enhances the bactericidal activity of iodine, reduces vapor pressure and odor. Staining is almost nonexistent and wide dilution with water is possible. Examples of prepn: Shelanski, Winicov, US 2710277 (1955 to West Labs); Scheib et al., US 2977315 (1961 to Lazarus Labs). Germicidal activity: C. A. Lawrence et al., J. Am. Pharm. Assoc. 46, 500 (1957). Reviews of manufacture, properties and use: D. R. Batey, Aust. J. Dairy Technol. 31, 5-7 (1976); A. Leitmanova et al., Pharmazie 42, 809-813 (1987).

Use

Germicide.

Therapeutic Category

Antiseptic; disinfectant.

Therapeutic Category (Veterinary)

Antiseptic; disinfectant.