5261. Jatrorrhizine

Nomenclature

CAS number: 3621-38-3
5,6-Dihydro-3-hydroxy-2,9,10-trimethoxydibenzo[a,g]quinolizinium; 7,8,13,13a-tetradehydro-3-hydroxy-2,9,10-trimethoxyberbinium; jateorrhizine; neprotin.
[C20H20NO4]+.

Description and references

From root of Jateorhiza palmata (DC.) Miers (J. columba Miers), Menispermaceae: Feist, Arch. Pharm. 245, 586 (1907); from Berberis asiatica Roxb. ex DC. and B. thunbergii DC., Berberidaceae: Chatterjee et al., J. Indian Chem. Soc. 31, 83 (1954); Tomita, Kikuchi, J. Pharm. Soc. Jpn. 76, 597 (1956); from Coptis teeta Wall., Ranunculaceae: Chatterjee et al., J. Indian Chem. Soc. 29, 97 (1952); from Mahonia acanthifolia Wall., M. borealis Takeda and M. simonsii Takeda, Berberidaceae: Chatterjee, Guha, J. Am. Pharm. Assoc. 39, 577 (1950); Chatterjee et al., ibid. 40, 36 (1951). Structure: Spth, Duschinsky, Ber. 58, 1939 (1925).

Chemical structure

Derivative

Iodide.
C20H20INO4; mol wt 465.28.
C 51.63%, H 4.33%, I 27.27%, N 3.01%, O 13.75%.

Properties

Reddish-yellow needles, mp 208-210°. Sol in water and alcohol.