Description and references

Lignans from various species of Justicia, Acanthaceae. Isoln and structures for justicidins A, B, C, D, E and F have been elucidated. Isoln of A and B: Munakata et al., Tetrahedron Lett. 1965, 4167; Ohta et al., Agric. Biol. Chem. 33, 610 (1969); Okigawa et al., Tetrahedron 26, 4301 (1970). Structure of A: Govindachari et al., Tetrahedron Lett. 1967, 3517; Horii et al., Chem. Pharm. Bull. 19, 535 (1971). Synthesis of B: Munakata et al., Tetrahedron Lett. 1967, 2831; Munakata, Katsura, GB 1178341 (1970), C.A. 72, 100365c; T. Momose et al., Chem. Pharm. Bull. 26, 3195 (1978). Isoln and structures of C and D: Ohta, Munakata, Tetrahedron Lett. 1970, 923. Synthesis of C: Horii et al., Chem. Pharm. Bull. 17, 1878 (1969). Structure of E: Wada, Munakata, Tetrahedron Lett. 1970, 2017. Synthesis of E: Holmes, Stevenson, J. Org. Chem. 36, 3450 (1971). Synthesis of D, E, and F: Z. I. Horii et al., Chem. Pharm. Bull. 25, 1803 (1977).

Derivative

Derivative