5361. Lanreotide

Nomenclature

CAS number: 108736-35-2
3-(2-Naphthalenyl)-d-alanyl-l-cysteinyl-l-tyrosyl-d-tryptophyl-l-lysyl-l-valyl-l-cysteinyl-l-threoninamide cyclic (2→7)-disulfide; angiopeptin; DC 13-116; BIM-23014.
C54H69N11O10S2; mol wt 1096.32.
C 59.16%, H 6.34%, N 14.05%, O 14.59%, S 5.85%.

Description and references

Octapeptide somatostatin analog. Prepn: D. H. Coy et al., EP 215171; eidem, US 4853371 (1987, 1989 both to Tulane Educational Fund). Clinical pharmacokinetics and hormonal effects: J. M. Kuhn et al., Br. J. Clin. Pharmacol. 38, 213 (1994). Clinical evaluation in acromegaly: P. Caron et al., Eur. J. Endocrinol. 132, 320 (1995).

Chemical structure

Derivative

Acetate.

Nomenclature

CAS number: 127984-74-1
BIM-23014C; Somatuline LP (Ipsen).
C54H69N11O10S2.xC2H4O2.

Therapeutic Category

Antineoplastic.

Keywords

Antineoplastic (Hormonal); Somatostatin Analog; Somatostatin Analog