5388. Laurotetanine

Nomenclature

CAS number: 128-76-7
(6aS)-5,6,6a,7-Tetrahydro-1,2,10-trimethoxy-4H-dibenzo[de,g]quinolin-9-ol; 1,2,10-trimethoxy-6aα-noraporphin-9-ol; Litsoeine.
C19H21NO4; mol wt 327.37.
C 69.71%, H 6.47%, N 4.28%, O 19.55%.

Description and references

From the bark of Litsea citrata Blume (Tetranthera citrata (Blume) Nees), Lauraceae and allied plants. Isoln: Greshoff, Ber. 23, 3537 (1890); Filippo, Arch. Pharm. 236, 601 (1898). Structure: Barger et al., Ber. 66, 450 (1933). Synthesis: Kikkawa, C.A. 53, 17163i (1959).

Chemical structure

Derivative

Monohydrate.

Properties

Needles, mp 125°. [α]D25 +98.5°. Practically insol in water. Freely sol in alcohol, chloroform, ethyl acetate, slightly in ether.