5559. Loflucarban

Nomenclature

CAS number: 790-69-2
N-(3,5-Dichlorophenyl)-N′-(4-fluorophenyl)thiourea; 3,5-dichloro-4′-fluorothiocarbanilide; Fluonilid (Continental Pharma).
C13H9Cl2FN2S; mol wt 315.19.
C 49.54%, H 2.88%, Cl 22.50%, F 6.03%, N 8.89%, S 10.17%.

Description and references

Prepd from p-fluorophenyl isothiocyanate and 3,5-dichloroaniline or from 3,5-dichlorophenyl isothiocyanate and p-fluoroaniline: BE 613154 (1962 to Madan), C.A. 58, 474f (1963).

Chemical structure

Properties

Crystals from ethanol, mp 148°. Soluble in ethyl oleate, isopropyl myristate.

Therapeutic Category

Antifungal.

Keywords

Antifungal (Synthetic)