5610. Luprostiol
Nomenclature
CAS number: 73523-00-9
(5Z)-7-[(1S,2R,3R,5S)-2-[[(2S)-3-(3-Chlorophenoxy)-2-hydroxypropyl]thio]-3,5-dihydroxycyclopentyl]-5-heptenoic
acid; 9α,11α,15-trihydroxy-16-m-chlorophenoxy-13-thia-17,18,19,20-tetranor-5-prostenoic
acid; prostianol; EMD-34946; Prosolvin (Intervet); Reprodin (Bayer). C21H29ClO6S; mol wt 444.97.
C 56.68%, H 6.57%, Cl 7.97%, O 21.57%, S 7.21%.
Description and references
Analog of prostaglandin F2α, q.v. Prepn: J. Kraemer et al., DE 2513371 (1976 to E. Merck), C.A. 86, 55069k (1977); eidem, US 4309441 (1982 to E. Merck). Luteolytic study in cattle: H. De Vries, H. Feenstra, J. Vet. Pharmacol. Ther. 2, 223 (1979). Estrus cycle regulation: D. Schams, H. Karg, Theriogenology 17, 499 (1982), C.A. 97, 50430p (1982).
