5995. 10-Methoxyharmalan

Nomenclature

CAS number: 3589-73-9
4,9-Dihydro-6-methoxy-1-methyl-3H-pyrido[3,4-b]indole; 1-methyl-6-methoxy-3,4-dihydro-2-carboline; 3,4-dihydromethoxyharman.
C13H14N2O; mol wt 214.26.
C 72.87%, H 6.59%, N 13.07%, O 7.47%.

Description and references

Prepn from 5-methoxytryptamine: Spth, Lederer, Ber. 63, 2102 (1930); Petrova et al., Zh. Obshch. Khim. 33, 1333 (1963), C.A. 59, 10149b (1963). Weak serotonin inhibitor: M. M. Airaksinen et al., Acta Pharmacol. Toxicol. 46, 308 (1980).

Chemical structure

Properties

Crystals, mp 208-209°. Rf 0.74 in 4:1:5 butanol, acetic acid, water.