6323. Mycobacillin

Nomenclature

CAS number: 18524-67-9
C65H85N13O30; mol wt 1528.44.
C 51.08%, H 5.61%, N 11.91%, O 31.40%.

Description and references

Antifungal polypeptide antibiotic isolated from culture filtrates of Bacillus subtilis: Majumdar, Bose, Nature 181, 134 (1958). Structural studies: eidem, Biochem. J. 74, 596 (1960); Arch. Biochem. Biophys. 90, 154 (1960). Amino acid configuration: Banerjee, Bose, Nature 200, 471 (1963). Nature of the peptide linkages: Sengupta et al., Biochem. J. 121, 839 (1971). Review: Banerjee et al., Antibiotics vol. II, D. Gottlieb, P. D. Shaw, Eds. (Springer-Verlag, New York, 1967) pp 271-275, 445-446.

Chemical structure

Properties

Needles, mp 235-240°. uv max 277 nm in a solution of n-butanol-water-acetic acid-95% ethanol (10:10:2:2).