6628. 2-Nitropropane

Nomenclature

CAS number: 79-46-9
1-Methylnitroethane; dimethylnitromethane; isonitropropane.
C3H7NO2; mol wt 89.09.
C 40.44%, H 7.92%, N 15.72%, O 35.92%.

Description and references

Prepn: Hass et al., US 1967667 (1934 to Purdue Res. Found.); Ind. Eng. Chem. 28, 339 (1936) DOI; from natural gas: Bachman, Pollack, ibid. 46, 713 (1954) DOI. Toxicity and carcinogenicity study: T. R. Lewis et al., J. Environ. Pathol. Toxicol. 2, 233 (1979) PubMed. Health hazard alert: Am. Ind. Hyg. Assoc. J. 41, 18 (1980).

Chemical structure

Properties

Colorless, oily liquid. Flammable. d425 0.9821. wt 8.4 lb/U.S. gal. mp -93°. bp760 120.3°; bp564 110°; bp300 90°; bp95 60°; bp7 10°. nD20 1.3944. Flash pt (closed cup): 24°C (75°F). Heat of formn -43.78 kcal/mole at 25°; heat of combustion 477.60 kcal/mole at 25°. Latent heat of vaporization 9.88 kcal/mole at 25°. Slightly sol in water (1.7 ml/100 ml); 0.6 ml water dissolves in 100 ml of 2-nitropropane. Misc with many organic solvents.

Caution

Potential symptoms of overexposure are headache, anorexia, nausea, vomiting, diarrhea; irritation of eyes, skin, nose and respiratory system; kidney and liver damage. See NIOSH Pocket Guide to Chemical Hazards (DHHS/NIOSH 97-140, 1997) p 230. This substance is reasonably anticipated to be a human carcinogen: Report on Carcinogens, Eleventh Edition (PB2005-104914, 2004) p III-194.

Use

Solvent in inks, paints, adhesives, varnishes, polymers, synthetic material; as chemical intermediate.