6635. N-Nitrosodiethanolamine
Nomenclature
CAS number: 1116-54-7
2,2′-(Nitrosoimino)bisethanol; diethanolnitrosamine; 2,2′-nitrosiminodiethanol; di-(2-hydroxyethyl)nitrosamine; NDELA. C4H10N2O3; mol wt 134.13.
C 35.82%, H 7.51%, N 20.89%, O 35.78%.
Description and references
Formed by the action of nitrites on di- or triethanolamine. Prepn: E. R. H. Jones, W. Wilson, J. Chem. Soc. 1949, 547; R. Preussmann, Ber. 95, 1571 (1962); W. Lijinsky et al., J. Natl. Cancer Inst. 49, 1239 (1972). Carcinogenicity study: H. Druckery et al., Z. Krebsforsch. 69, 103 (1967). Impurity in cutting fluids: T. Y. Fan et al., Science 196, 70 (1977); in cosmetics: eidem, Food Cosmet. Toxicol. 15, 423 (1977). Mutagenicity study: A. Hesbert et al., Mutat. Res. 68, 207 (1979).
