6665. Nocardamin

Nomenclature

CAS number: 26605-16-3
1,12,23-Trihydroxy-1,6,12,17,23,28-hexaazacyclotritriacontane-2,5,13,16,24,27-hexone.
C27H48N6O9; mol wt 600.70.
C 53.99%, H 8.05%, N 13.99%, O 23.97%.

Description and references

Antibiotic substance produced by a Nocardia isolated from old bee-honeycombs: Stoll et al., Schweiz. Z. Pathol. Bakteriol. 14, 225 (1951); Helv. Chim. Acta 34, 862 (1951). Structure: Keller-Schierlein, Prelog, ibid. 44, 1981 (1961).

Chemical structure

Properties

Needles from hot methanol, mp 192-195°. Optically inactive. Has no basic properties. Soluble in hot water, methanol. An 0.5% aq soln at room temp has a pH of 4.55.

Derivative

Triacetate.
C33H54N6O12; mol wt 726.81.
C 54.53%, H 7.49%, N 11.56%, O 26.42%.

Properties

Crystals, mp 115-117°.