6685. Noracymethadol

Nomenclature

CAS number: 1477-39-0
α-Ethyl-β-[2-(methylamino)propyl]-β-phenylbenzeneethanol acetate; α-dl-6-(methylamino)-4,4-diphenyl-3-heptanol acetate; α-dl-3-acetoxy-4,4-diphenyl-6-methylaminoheptane; α-dl-3-acetoxy-6-methylamino-4,4-diphenylheptane; α-dl-4,4-diphenyl-6-methylamino-3-heptanol acetate.
C22H29NO2; mol wt 339.47.
C 77.84%, H 8.61%, N 4.13%, O 9.43%.

Description and references

Metabolite of methadyl acetate, q.v. Prepn: A. Pohland, US 3021360 (1962 to Lilly). Metabolism: G. L. Henderson et al., Drug Metab. Dispos. 5, 321 (1977); M. Man et al., ibid. 8, 55 (1980). HPLC determn: C.-H. Kiang et al., J. Chromatogr. 222, 81 (1981).

Chemical structure

Derivative

Hydrochloride.

Nomenclature

CAS number: 5633-25-0
NIH-7667.
C22H29NO2.HCl; mol wt 375.93.
C 70.29%, H 8.04%, N 3.73%, O 8.51%, Cl 9.43%.

Properties

Crystals from acetone + ether, mp ≈216-217°.

Note

This is a controlled substance (opiate): 21 CFR, 1308.11.