6696. Norethandrolone

Nomenclature

CAS number: 52-78-8
(17α)-17-Hydroxy-19-norpregn-4-en-3-one; 17α-ethyl-19-nortestosterone; 17α-ethyl-17-hydroxy-4-norandrosten-3-one; 17α-ethyl-17-hydroxy-19-norandrost-4-en-3-one; Nilevar (Searle); Solevar.
C20H30O2; mol wt 302.45.
C 79.42%, H 10.00%, O 10.58%.

Description and references

Prepn by catalytic hydrogenation of 17α-ethynyl-19-nortestosterone: Colton, US 2721871 (1955 to Searle); J. Am. Chem. Soc. 79, 1123 (1957).

Chemical structure

Properties

Crystals from methanol, mp 140-141°. uv max: 240 nm (ε 16500). Sol in alcohol, benzene, ether, ethyl acetate. Insol in water.

Note

This is a controlled substance (anabolic steroid): 21 CFR, 1308.13, as defined in 1300.01.

Therapeutic Category

Androgen.

Keywords

Androgen