6851. Opianic Acid

Nomenclature

CAS number: 519-05-1
6-Formyl-2,3-dimethoxybenzoic acid; 5,6-dimethoxyphthalaldehydic acid.
C10H10O5; mol wt 210.18.
C 57.14%, H 4.80%, O 38.06%.

Description and references

Obtained (together with cotarnine) by heating narcotine with dil HNO3. Prepn: Wilson et al., J. Org. Chem. 16, 792 (1951); Blair, J. Chem. Soc. 1955, 708. NMR studies: Buu-Hoi et al., Bull. Soc. Chim. Fr. 1970, 137.

Chemical structure

Properties

Needles from water, mp 150°. Sol in 400 parts cold, 60 parts boiling water; sol in alcohol, ether. uv max: 215, 284 nm (ε 20,700, 6500).