6930. Oxeladin

Nomenclature

CAS number: 468-61-1
α,α-Diethylbenzeneacetic acid 2-[2-(diethylamino)ethoxy]ethyl ester; 2-ethyl-2-phenylbutyric acid 2-(2-diethylaminoethoxy)ethyl ester; 2-(2-diethylaminoethoxy)ethyl α,α-diethylphenylacetate; α,α-diethylphenylacetic acid 2-(2-diethylaminoethoxy)ethyl ester.
C20H33NO3; mol wt 335.48.
C 71.60%, H 9.91%, N 4.18%, O 14.31%.

Description and references

Prepn: V. Petrow et al., J. Pharm. Pharmacol. 10, 40 (1958); eidem, US 2885404 (1959 to Brit. Drug Houses).

Chemical structure

Properties

Yellow oil with an acrid odor and bitter taste. bp0.5 150°; bp0.1 140°. Soluble in dil HCl, ethanol, acetone, ether, toluene; practically insol in water. Stable in acids, unstable in alkalies. Non-hygroscopic.

Derivative

Citrate.

Nomenclature

CAS number: 52432-72-1
Pectamol (BDH); Pectamon; Paxeladine (Beaufour).
C20H33NO3.C6H8O7; mol wt 527.60.
C 59.19%, H 7.83%, N 2.65%, O 30.32%.

Properties

Small needles from ethyl acetate, mp 90-91°. Sol in water.

Therapeutic Category

Antitussive.

Keywords

Antitussive