6970. Oxypendyl

Nomenclature

CAS number: 5585-93-3
4-[3-(10H-Pyrido[3,2-b][1,4]benzothiazin-10-yl)propyl]-1-piperazineethanol; 10-[3-[4-(2-hydroxyethyl)-1-piperazinyl]propyl]-10H-pyrido[3,2-b][1,4]benzothiazine; 10-[3-(1-hydroxyethyl-4-piperazinyl)propyl]-4-azaphenothiazine; oxipendyl; D-706.
C20H26N4OS; mol wt 370.51.
C 64.83%, H 7.07%, N 15.12%, O 4.32%, S 8.65%.

Description and references

Prepn: Schuler, Klebe, Ann. 653, 172 (1962).

Chemical structure

Properties

bp1 260-265°, bp6 280-300°.

Derivative

Dihydrochloride.

Nomenclature

CAS number: 17297-82-4
Pervetral (Viatris).
C20H26N4OS.2HCl; mol wt 443.43.
C 54.17%, H 6.36%, N 12.63%, O 3.61%, S 7.23%, Cl 15.99%.

Properties

Crystals, mp 218-220°.

Therapeutic Category

Antiemetic.

Keywords

Antiemetic