6995. Palmidrol

Nomenclature

CAS number: 544-31-0
N-(2-Hydroxyethyl)hexadecanamide; N-(2-hydroxyethyl)palmitamide.
C18H37NO2; mol wt 299.49.
C 72.19%, H 12.45%, N 4.68%, O 10.68%.
CH3(CH2)14CONHCH2CH2OH.

Description and references

A naturally occurring anti-inflammatory agent. Isolated from soybean lecithin, egg yolk, and peanut meal: Kuehl et al., J. Am. Chem. Soc. 79, 5577 (1957). Synthesis by refluxing ethanolamine with palmitic acid: Roe et al., ibid. 74, 3442 (1952).

Properties

Crystals from 95% ethanol or cyclohexane, mp 98-99°.