7095. Penicillin G Benethamine

Nomenclature

CAS number: 751-84-8
(2S,5R,6R)-3,3-Dimethyl-7-oxo-6-[(phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid compd with N-(phenylmethyl)benzeneethanamine (1:1); benzylpenicillinic acid N-benzyl-β-phenylethylamine salt; benethamine penicillin G.
C31H35N3O4S; mol wt 545.69.
C 68.23%, H 6.46%, N 7.70%, O 11.73%, S 5.88%.

Description and references

Repository form of penicillin G. Prepn: Jansen, Hems, GB 732559 (1955 to Glaxo). Clinical studies: Nelson et al., Br. Med. J. II, 339 (1954); Boger et al., Antibiot. Annu. 1954-55, 123.

Properties

Crystals, mp 146-147°. Slight, characteristic, amine taste. Very slightly sol in water (0.1 w/v at 40°).

Therapeutic Category (Veterinary)

Antibacterial.