7229. Phenetole

Nomenclature

CAS number: 103-73-1
Ethoxybenzene; ethyl phenyl ether; phenyl ethyl ether.
C8H10O; mol wt 122.16.
C 78.66%, H 8.25%, O 13.10%.
C6H5OC2H5.

Description and references

Prepd from phenol or its salts by the use of the ethylating agent ethyl chloride: Wohl, Ber. 39, 1953 (1906); ethyl bromide: White et al., J. Am. Chem. Soc. 46, 965 (1924); ethyl p-toluenesulfonate: Finzi, Ann. Chim. Appl. 15, 41 (1925); diethyl sulfate or triethyl phosphate: Noller, Dutton, J. Am. Chem. Soc. 55, 424 (1933). Toxicity data: Binet, Rev. Med. Suisse Romande 15, 561 (1895).

Properties

Oily liquid. d420 0.967; mp -30°; bp 171-173°; nD20 1.507. Practically insol in water. Freely sol in alcohol, ether. MLD in rats (mg/kg): 3500-4000 s.c. (Binet).