7234. Phenindione

Nomenclature

CAS number: 83-12-5
2-Phenyl-1H-indene-1,3(2H)-dione; 2-phenyl-1,3-indandione; 2-phenyl-1,3-diketohydrindene; PID; Pindione (Lipha); Bindan; Dindevan (Duncan Flockhart); Dineval; Hemolidione (Sintetico); Indon (Parke-Davis); Indema; Fenilin; Fenhydren; Rectadione; Cronodione; Thrombasal.
C15H10O2; mol wt 222.24.
C 81.07%, H 4.54%, O 14.40%.

Description and references

By heating phthalide with benzaldehyde and sodium ethylate soln: Dieckmann, Ber. 47, 1439 (1914).

Chemical structure

Properties

Leaflets from alcohol, mp 149-151°. Practically insol in cold water. Slightly sol in warm water. pH of satd soln at 25° = 4.5. Readily sol in alkaline solns. Soluble in methanol, ethanol, ether, acetone, benzene, chloroform. Solns in alkalies are red, in concd H2SO4 blue.

Therapeutic Category

Anticoagulant.

Keywords

Anticoagulant